DNA methylation changes following DNA damage in prostate cancer cells
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چکیده
منابع مشابه
DNA Methylation-Mediated Downregulation of DEFB1 in Prostate Cancer Cells
Epigenetic aberrations play crucial roles in prostate cancer (PCa) development and progression. The DEFB1 gene, which encodes human ß-defensin-1 (HBD-1), contributes to innate immune responses and functions as a potential tumor suppressor in urological cancers. We investigated whether differential DNA methylation at the low CpG-content promoter (LCP) of DEFB1 was associated with transcriptional...
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ژورنال
عنوان ژورنال: Epigenetics
سال: 2019
ISSN: 1559-2294,1559-2308
DOI: 10.1080/15592294.2019.1629231